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Retatrutide is Eli Lilly's “Triple G” A novel triple agonist for GIP, GLP1, and glucagon receptors. A 48 week phase 2 obesity study demonstrated 24.2% weight loss with retatrutide 12 mg with
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With retatrutide approaching ~30% weight loss at 2 years—but with what appears to be a meaningfully higher adverse event burden than earlier-generation incretin therapies—expert clinical guidance will matter even more. If you
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