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Are Serious Anesthesia Risks of Semaglutide and Other GLP-1 Agonists Under-Recognized? Case Reports of Retained Solid Gastric Contents in Patients Undergoing Anesthesia
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GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) have become incredibly common in diabetes and weight-management care, and they're now showing up more and more in the perioperative setting. These
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Patients taking the new class of weight-loss drugs do not need to stop these medications prior to procedures requiring anesthesia, but they should adhere to longer preoperative fasting times, according to a
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🇬🇧 Perioperative Management of New Popular Agents: GLP-1 Agonists (GLP-1 RA: semaglutide, tirzepatide) These drugs delay gastric emptying → patients may have a “full stomach” despite fasting This increases risk of regurgitation
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