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Late breaking at #ADA23: In this trial involving participants with obesity, 48 weeks of treatment with retatrutide, an agonist of the GIP, GLP-1, and GCG receptors, resulted in substantial reductions in body
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Great news again!!! A phase 2 trial of Retatrutide (Triple–Hormone-Receptor Agonist) for obesity. At 48 wks the median body weight loss was 24.2% and >5%, >10% and >15% had occurred in 100%,
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Retatrutide (not yet approved in US but people using anyway) promises even potentially greater weight loss amongst the GLP1 drugs. https://www.nejm .org/doi/full/10.1056/NEJMoa2301972
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Phase 2 Trial of Retatrutide for Obesity
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Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial @ NEJM Amazing 24% weight reduction with new obesity drug (-24.2% change in body weight at 48 weeks) Obesity treatment with Triple–Hormone-Receptor Agonist #
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Retatrutide Dosing Guide: 1-12 mg Weekly Triple Agonist (2026)
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Retatrutide just delivered one of the largest weight-loss signals we've ever seen in a medication trial. In a phase 2 study: • Up to 24.2% mean weight loss at 48 weeks •
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