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FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells
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Senolytics: charting a new course or enhancing existing anti-tumor therapies? | Cellular Oncology
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FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation
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Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells
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Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases
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A paper published in Cell investigated the effects of a FOXO4 peptide to target senescent cells in mice and reported improved kidney function and restoration of fur, suggesting that this could lead
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CHK2-USP37 axis stabilizes FOXO4 to sustain senescence and evade apoptosis
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